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The study also revealed that the screening ability of HbA1c in non-Hispanic Americans differed by race. For example, researchers observed more false- negative results and fewer false-positive results in whites than blacks.
Given that the proposed HbA1c diagnostic for screening are both insensitive and racially discrepant, what is the optimal way to screen for diabetes? Dr. Rhee recommended that doctors perform the standard 75 gram OGTT, or, at the very least, a fasting glucose level followed by the OGTT in individuals whose levels are abnormal (100 mg/dL and above). |
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